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In vivo Studies on Pharmacokinetics, Toxicity and Immunogenicity of Polyelectrolyte Nanocapsules Functionalized with Two Different Polymers: Poly-L-Glutamic Acid or PEG

BACKGROUND: The functionalization of a nanoparticle surface with PEG (polyethylene glycol) is an approach most often used for extending nanomaterial circulation time, enhancing its delivery and retention in the target tissues, and decreasing systemic toxicity of nanocarriers and their cargos. Howeve...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Karabasz, Alicja, Szczepanowicz, Krzysztof, Cierniak, Agnieszka, Mezyk-Kopec, Renata, Dyduch, Grzegorz, Szczęch, Marta, Bereta, Joanna, Bzowska, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901045/
https://ncbi.nlm.nih.gov/pubmed/31824153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S230865
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