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In vivo Studies on Pharmacokinetics, Toxicity and Immunogenicity of Polyelectrolyte Nanocapsules Functionalized with Two Different Polymers: Poly-L-Glutamic Acid or PEG

BACKGROUND: The functionalization of a nanoparticle surface with PEG (polyethylene glycol) is an approach most often used for extending nanomaterial circulation time, enhancing its delivery and retention in the target tissues, and decreasing systemic toxicity of nanocarriers and their cargos. Howeve...

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Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Karabasz, Alicja, Szczepanowicz, Krzysztof, Cierniak, Agnieszka, Mezyk-Kopec, Renata, Dyduch, Grzegorz, Szczęch, Marta, Bereta, Joanna, Bzowska, Monika
Format: Artigo
Langue:Inglês
Publié: Dove 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901045/
https://ncbi.nlm.nih.gov/pubmed/31824153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S230865
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