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Self-Assembled pH-Sensitive Cholesteryl Pullulan Nanogel As a Protein Delivery Vehicle

A self-assembled nanogel, derived from an acidl-abile cholesteryl-modified pullulan (acL-CHP), was prepared by grafting vinyl ether-cholesterol substituents onto a 100 kD pullulan main chain polymer backbone. Stable nanogels are formed by acL-CHP self-assemblies at neutral pH. The hydrodynamic radiu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomacromolecules
Hauptverfasser: Morimoto, Nobuyuki, Hirano, Sayaka, Takahashi, Haruko, Loethen, Scott, Thompson, David H., Akiyoshi, Kazunari
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900930/
https://ncbi.nlm.nih.gov/pubmed/23215439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm301286h
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