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Structural effects and lymphocyte activation properties of self-assembled polysaccharide nanogels for effective antigen delivery
The success of immunotherapeutic vaccines is often limited by their inability to activate the cytotoxic T lymphocyte (CTL)-inducing Th1 pathway. We investigated the ability of self-assembled nanogels (CHP or CH-CDex) to activate this pathway, and characterised them chemically and biologically. Once...
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| Publicado no: | Sci Rep |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6220277/ https://ncbi.nlm.nih.gov/pubmed/30405172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34885-8 |
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