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Mechanisms of immune-related adverse events during the treatment of cancer with immune checkpoint inhibitors

Immune checkpoint inhibitors are novel biologic agents to treat cancer by inhibiting the regulatory interactions that limit T cell cytotoxicity to tumours. Current agents target either CTLA-4 or the PD-1/PD-L1 axis. Because checkpoints may also regulate autoreactivity, immune checkpoint inhibitor th...

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Detaylı Bibliyografya
Yayımlandı:Rheumatology (Oxford)
Asıl Yazarlar: Weinmann, Sophia C, Pisetsky, David S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900913/
https://ncbi.nlm.nih.gov/pubmed/31816080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kez308
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