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Mechanisms of immune-related adverse events during the treatment of cancer with immune checkpoint inhibitors
Immune checkpoint inhibitors are novel biologic agents to treat cancer by inhibiting the regulatory interactions that limit T cell cytotoxicity to tumours. Current agents target either CTLA-4 or the PD-1/PD-L1 axis. Because checkpoints may also regulate autoreactivity, immune checkpoint inhibitor th...
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| Publicado no: | Rheumatology (Oxford) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900913/ https://ncbi.nlm.nih.gov/pubmed/31816080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kez308 |
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