Inhibition of Endocytosis of Clathrin-Mediated Angiotensin II Receptor Type 1 in Podocytes Augments Glomerular Injury

BACKGROUND: Inhibition of the renin-angiotensin system remains a cornerstone in reducing proteinuria and progression of kidney failure, effects believed to be the result of reduction in BP and glomerular hyperfiltration. However, studies have yielded conflicting results on whether podocyte-specific...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Inoue, Kazunori, Tian, Xuefei, Velazquez, Heino, Soda, Keita, Wang, Zhen, Pedigo, Christopher E., Wang, Ying, Cross, Elizabeth, Groener, Marwin, Shin, Jee-Won, Li, Wei, Hassan, Hossam, Yamamoto, Koichi, Mundel, Peter, Ishibe, Shuta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900791/
https://ncbi.nlm.nih.gov/pubmed/31511362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019010053
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