Anti-donor MHC Class II Alloantibody Induces Glomerular Injury in Mouse Renal Allografts Subjected to Prolonged Cold Ischemia

BACKGROUND: The mechanisms underlying the effects of prolonged cold-ischemia storage on kidney allografts are poorly understood. METHODS: To investigate effects of cold ischemia on donor-reactive immune responses and graft pathology, we used a mouse kidney transplantation model that subjected MHC-mi...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Gorbacheva, Victoria, Fan, Ran, Beavers, Ashley, Fairchild, Robert L., Baldwin, William M., Valujskikh, Anna
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2019
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900787/
https://ncbi.nlm.nih.gov/pubmed/31597715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018111169
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