Vitamin D binding protein is required to utilize skin-generated vitamin D

Vitamin D is produced in the skin following exposure to sunlight. Ultraviolet (UV) B (UVB, 280–310 nm) results in isomerization of 7-dehydrocholesterol to previtamin D that spontaneously isomerizes to vitamin D. This pool of skin-derived vitamin D is the major source of vitamin D for animals. Howeve...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Duchow, Elizabeth G., Cooke, Nancy E., Seeman, Jeremy, Plum, Lori A., DeLuca, Hector F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900711/
https://ncbi.nlm.nih.gov/pubmed/31748273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915442116
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