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Clustering and dynamics of crowded proteins near membranes and their influence on membrane bending

Atomistic molecular dynamics simulations of concentrated protein solutions in the presence of a phospholipid bilayer are presented to gain insights into the dynamics and interactions at the cytosol–membrane interface. The main finding is that proteins that are not known to specifically interact with...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Nawrocki, Grzegorz, Im, Wonpil, Sugita, Yuji, Feig, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900600/
https://ncbi.nlm.nih.gov/pubmed/31740611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910771116
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