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Effect of Protein-Protein Interactions and Solvent Viscosity on the Rotational Diffusion of Proteins in Crowded Environments
The rotational diffusion of a protein in the presence of protein crowder molecules was analyzed via computer simulations. Cluster formation as a result of transient intermolecular contacts was identified as the dominant effect for reduced rotational diffusion upon crowding. The slow-down in diffusio...
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| Published in: | Phys Chem Chem Phys |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6322922/ https://ncbi.nlm.nih.gov/pubmed/30560249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cp06142d |
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