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Reduced native state stability in crowded cellular environment due to protein-protein interactions
The effect of cellular crowding environments on protein structure and stability is a key issue in molecular and cellular biology. The classical view of crowding emphasizes the volume exclusion effect that generally favors compact, native states. Here, results from molecular dynamics simulations and...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601481/ https://ncbi.nlm.nih.gov/pubmed/23402619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3126992 |
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