Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET)

The sigma-1 receptor (σ(1)R) is a unique intracellular protein. σ(1)R plays a major role in various pathological conditions in the central nervous system (CNS), implicated in several neuropsychiatric disorders. Imaging of σ(1)R in the brain using positron emission tomography (PET) could serve as a n...

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Veröffentlicht in:Acta Pharm Sin B
Hauptverfasser: Lan, Yu, Bai, Ping, Chen, Zude, Neelamegam, Ramesh, Placzek, Michael S., Wang, Hao, Fiedler, Stephanie A., Yang, Jing, Yuan, Gengyang, Qu, Xiying, Schmidt, Hayden R., Song, Jinchun, Normandin, Marc D., Ran, Chongzhao, Wang, Changning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900558/
https://ncbi.nlm.nih.gov/pubmed/31867166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.07.002
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