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ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism
Inositol phosphates (IPs) comprise a network of phosphorylated molecules that play multiple signaling roles in eukaryotes. IPs synthesis is believed to originate with IP(3) generated from PIP(2) by phospholipase C (PLC). Here, we report that in mammalian cells PLC-generated IPs are rapidly recycled...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900528/ https://ncbi.nlm.nih.gov/pubmed/31754032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911431116 |
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