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ITPK1 mediates the lipid-independent synthesis of inositol phosphates controlled by metabolism
Inositol phosphates (IPs) comprise a network of phosphorylated molecules that play multiple signaling roles in eukaryotes. IPs synthesis is believed to originate with IP(3) generated from PIP(2) by phospholipase C (PLC). Here, we report that in mammalian cells PLC-generated IPs are rapidly recycled...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900528/ https://ncbi.nlm.nih.gov/pubmed/31754032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911431116 |
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