IL-12/IL-23 neutralization is ineffective for alopecia areata in mice and humans

Ustekinumab is currently being explored for the treatment of alopecia areata. Here, our work in a murine model and in human patients indicates that neutralization of the IL-12 and IL-23 pathways does not ameliorate disease.

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Dades bibliogràfiques
Publicat a:J Allergy Clin Immunol
Autors principals: Ortolan, Luana S., Kim, Sa Rang, Crotts, Sydney, Liu, Lucy Y., Craiglow, Brittany G., Wambier, Carlos, Paschoal, Renato S., King, Brett A., Jabbari, Ali
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900443/
https://ncbi.nlm.nih.gov/pubmed/31470035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.08.014
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