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IL-12/IL-23 neutralization is ineffective for alopecia areata in mice and humans
Ustekinumab is currently being explored for the treatment of alopecia areata. Here, our work in a murine model and in human patients indicates that neutralization of the IL-12 and IL-23 pathways does not ameliorate disease.
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| Publicado no: | J Allergy Clin Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900443/ https://ncbi.nlm.nih.gov/pubmed/31470035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.08.014 |
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