A Phenotypic Switch of Differentiated Glial Cells to Dedifferentiated Cells Is Regulated by Folate Receptor α

In a previous study, we showed that folate receptor‐α (FRα) translocates to the nucleus where it acts as a transcription factor and upregulates Hes1, Oct4, Sox2, and Klf4 genes responsible for pluripotency. Here, we show that acetylation and phosphorylation of FRα favor its nuclear translocation in...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Monick, Sarah, Mohanty, Vineet, Khan, Mariam, Yerneni, Gowtham, Kumar, Raj, Cantu, Jorge, Ichi, Shunsuke, Xi, Guifa, Singh, Bal Ram, Tomita, Tadanori, Mayanil, Chandra Shekhar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Tissue‐Specific Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899875/
https://ncbi.nlm.nih.gov/pubmed/31381815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3067
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