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Erythropoietin-mediated activation of aquaporin-4 channel for the treatment of experimental hydrocephalus

OBJECTIVE: In this study, we investigate a neuroprotective agent, erythropoietin (EPO), in animal hydrocephalus model and its potential reversal effects on hydrocephalus by altering the expression of aquaporin-4 (AQP4). METHODS: Obstructive hydrocephalus was induced in 2-week-old rat pups by injecti...

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Detalhes bibliográficos
Publicado no:Childs Nerv Syst
Main Authors: Rizwan Siddiqui, M., Attar, Furqan, Mohanty, Vineet, Kim, Kwang Sik, Shekhar Mayanil, C., Tomita, Tadanori
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208663/
https://ncbi.nlm.nih.gov/pubmed/29982881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00381-018-3865-z
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