Monitoring translation in synaptic fractions using a ribosome profiling strategy

BACKGROUND: The aim of this study was to develop a method to study genome-wide local translation in biochemically isolated synaptic fractions (synaptoneurosomes). This methodology is of particular interest for neurons, due to the cardinal role of local translational control in neuronal sub-compartme...

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Publicat a:J Neurosci Methods
Autors principals: Simbriger, Konstanze, Amorim, Inês S., Chalkiadaki, Kleanthi, Lach, Gilliard, Jafarnejad, Seyed Mehdi, Khoutorsky, Arkady, Gkogkas, Christos G.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier/North-Holland Biomedical Press 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899497/
https://ncbi.nlm.nih.gov/pubmed/31610213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2019.108456
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