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Helix N-Cap Residues Drive the Acid Unfolding That Is Essential in the Action of the Toxin Colicin A
[Image: see text] Numerous bacterial toxins and other virulence factors use low pH as a trigger to convert from water-soluble to membrane-inserted states. In the case of colicins, the pore-forming domain of colicin A (ColA-P) has been shown both to undergo a clear acidic unfolding transition and to...
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| 發表在: | Biochemistry |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2019
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6899464/ https://ncbi.nlm.nih.gov/pubmed/31686499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00705 |
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