TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions

MAIT cells are an unconventional T cell population that can be activated through both TCR-dependent and TCR-independent mechanisms. Here, we examined the impact of combinations of TCR-dependent and TCR-independent signals in human CD8(+) MAIT cells. TCR-independent activation of these MAIT cells fro...

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Publicado no:Cell Rep
Main Authors: Leng, Tianqi, Akther, Hossain Delowar, Hackstein, Carl-Philipp, Powell, Kate, King, Thomas, Friedrich, Matthias, Christoforidou, Zoe, McCuaig, Sarah, Neyazi, Mastura, Arancibia-Cárcamo, Carolina V., Hagel, Joachim, Powrie, Fiona, Peres, Raphael Sanches, Millar, Val, Ebner, Daniel, Lamichhane, Rajesh, Ussher, James, Hinks, Timothy S.C., Marchi, Emanuele, Willberg, Chris, Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899450/
https://ncbi.nlm.nih.gov/pubmed/31533032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.08.050
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