Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions

Amino acid availability in Gram-positive bacteria is monitored by T-box riboswitches. T-boxes directly bind tRNAs, assess their aminoacylation state, and regulate the transcription or translation of downstream genes to maintain nutritional homeostasis. Here, we report co-crystal and cryo-EM structur...

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Publicado en:Nat Struct Mol Biol
Main Authors: Li, Shuang, Su, Zhaoming, Lehmann, Jean, Stamatopoulou, Vassiliki, Giarimoglou, Nikoleta, Henderson, Frances E., Fan, Lixin, Pintilie, Grigore D., Zhang, Kaiming, Chen, Muyuan, Ludtke, Steven J., Wang, Yun-Xing, Stathopoulos, Constantinos, Chiu, Wah, Zhang, Jinwei
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899168/
https://ncbi.nlm.nih.gov/pubmed/31740854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0326-7
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