The association between BMI and BSA–temozolomide-induced myelosuppression toxicities: a correlative analysis of NRG oncology RTOG 0525

BACKGROUND: Fearing increased myelotoxicity, many practitioners adjust the body surface area (BSA)-calculated doses in obese patients. Regarding temozolomide (TMZ), a prior study suggested men with a BSA >2 m(2) may experience increased toxicity; however, surprisingly, the inverse observation was...

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Pubblicato in:Neurooncol Pract
Autori principali: Robins, H Ian, Eickhoff, Jens, Gilbert, Mark R, Armstrong, Terri S, Shi, Wenyin, De Groot, John F, Schultz, Christopher J, Hunter, Grant K, Valeinis, Egils, Roach, Mack, Youssef, Emad F, Souhami, Luis, Howard, Steve P, Lieberman, Frank S, Herman, James G, Zhang, Peixin, Mehta, Minesh P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899045/
https://ncbi.nlm.nih.gov/pubmed/31832217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nop/npz006
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