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The association between BMI and BSA–temozolomide-induced myelosuppression toxicities: a correlative analysis of NRG oncology RTOG 0525

BACKGROUND: Fearing increased myelotoxicity, many practitioners adjust the body surface area (BSA)-calculated doses in obese patients. Regarding temozolomide (TMZ), a prior study suggested men with a BSA >2 m(2) may experience increased toxicity; however, surprisingly, the inverse observation was...

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Detalhes bibliográficos
Publicado no:Neurooncol Pract
Main Authors: Robins, H Ian, Eickhoff, Jens, Gilbert, Mark R, Armstrong, Terri S, Shi, Wenyin, De Groot, John F, Schultz, Christopher J, Hunter, Grant K, Valeinis, Egils, Roach, Mack, Youssef, Emad F, Souhami, Luis, Howard, Steve P, Lieberman, Frank S, Herman, James G, Zhang, Peixin, Mehta, Minesh P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899045/
https://ncbi.nlm.nih.gov/pubmed/31832217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nop/npz006
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