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Repression of an activity-dependent autocrine insulin signal is required for sensory neuron development in C. elegans

Nervous system development is instructed by genetic programs and refined by distinct mechanisms that couple neural activity to gene expression. How these processes are integrated remains poorly understood. Here, we report that the regulated release of insulin-like peptides (ILPs) during development...

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Publicat a:Development
Autors principals: Horowitz, Lauren Bayer, Brandt, Julia P., Ringstad, Niels
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899041/
https://ncbi.nlm.nih.gov/pubmed/31628111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.182873
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