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Repression of an activity-dependent autocrine insulin signal is required for sensory neuron development in C. elegans

Nervous system development is instructed by genetic programs and refined by distinct mechanisms that couple neural activity to gene expression. How these processes are integrated remains poorly understood. Here, we report that the regulated release of insulin-like peptides (ILPs) during development...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Horowitz, Lauren Bayer, Brandt, Julia P., Ringstad, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899041/
https://ncbi.nlm.nih.gov/pubmed/31628111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.182873
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