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A case report of two siblings with Alstrom syndrome without hearing loss associated with two new ALMS1 variants

BACKGROUND: Alström syndrome (AS) is a rare monogenic disorder characterized by progressive multi-organ pathology including retinal degeneration, hearing impairment and type 2 diabetes. Here we present clinical features in two siblings diagnosed with Alström syndrome associated with two novel change...

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Pubblicato in:BMC Ophthalmol
Autori principali: Shurygina, Maria F., Parker, Maria A., Schlechter, Catie L., Chen, Rui, Li, Yumei, Weleber, Richard G., Yang, Paul, Pennesi, Mark E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898930/
https://ncbi.nlm.nih.gov/pubmed/31810438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-019-1259-y
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