Adverse transverse-tubule remodeling in a rat model of heart failure is attenuated with low-dose triiodothyronine treatment

ABSTRACT: Pre-clinical animal studies have shown that triiodothyronine (T3) replacement therapy improves cardiac contractile function after myocardial infarction (MI). We hypothesized that T3 treatment could prevent adverse post-infarction cardiomyocyte remodeling by maintaining transverse-tubule (T...

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Bibliographic Details
Published in:Mol Med
Main Authors: An, Shimin, Gilani, Nimra, Huang, Yuan, Muncan, Adam, Zhang, Youhua, Tang, Yi-Da, Gerdes, A. Martin, Ojamaa, Kaie
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898920/
https://ncbi.nlm.nih.gov/pubmed/31810440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-019-0120-3
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