Chronic dantrolene treatment attenuates cardiac dysfunction and reduces atrial fibrillation inducibility in a rat myocardial infarction heart failure model

BACKGROUND: Cardiac ryanodine receptor 2 (RyR2) dysfunction and elevated diastolic Ca(2+) leak have been linked to arrhythmogenesis not only in inherited arrhythmia syndromes but also in acquired forms of heart disease including heart failure (HF) and atrial fibrillation (AF). Thus, stabilizing RyR2...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Heart Rhythm O2
Main Authors: Nofi, Colleen, Zhang, Kuo, Tang, Yi-Da, Li, Ying, Migirov, Allan, Ojamaa, Kaie, Gerdes, A. Martin, Zhang, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Experimental
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183840/
https://ncbi.nlm.nih.gov/pubmed/34113867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hroo.2020.03.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados