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Decoding pluripotency - genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency

Pluripotent stem cells have the ability to unlimitedly self-renew and differentiate to any somatic cell lineage. A number of systems biology approaches have been used to define this pluripotent state. Complementary to systems level characterization, genetic screens offer a unique avenue to functiona...

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Detalhes bibliográficos
Publicado no:Wiley Interdiscip Rev Syst Biol Med
Main Authors: Li, Qing V., Rosen, Bess P., Huangfu, Danwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898739/
https://ncbi.nlm.nih.gov/pubmed/31407519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1464
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