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NAIL-MS reveals the repair of 2-methylthiocytidine by AlkB in E. coli

RNAs contain post-transcriptional modifications, which fulfill a variety of functions in translation, secondary structure stabilization and cellular stress survival. Here, 2-methylthiocytidine (ms(2)C) is identified in tRNA of E. coli and P. aeruginosa using NAIL-MS (nucleic acid isotope labeling co...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Reichle, Valentin F., Petrov, Dimitar P., Weber, Verena, Jung, Kirsten, Kellner, Stefanie
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898146/
https://ncbi.nlm.nih.gov/pubmed/31811240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13565-9
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