Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer

Loss-of-function mutations of the breast cancer type 1 susceptibility protein (BRCA1) are associated with breast (BC) and ovarian cancer (OC). To identify gene signatures regulated by epigenetic mechanisms in OC cells carrying BRCA1 mutations, we assessed cellular responses to epigenome modifiers an...

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Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Cardenas, Horacio, Jiang, Guanglong, Thomes Pepin, Jessica, Parker, J. Brandon, Condello, Salvatore, Nephew, Kenneth P., Nakshatri, Harikrishna, Chakravarti, Debabrata, Liu, Yunlong, Matei, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897992/
https://ncbi.nlm.nih.gov/pubmed/31840082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0103-4
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