Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer

Loss-of-function mutations of the breast cancer type 1 susceptibility protein (BRCA1) are associated with breast (BC) and ovarian cancer (OC). To identify gene signatures regulated by epigenetic mechanisms in OC cells carrying BRCA1 mutations, we assessed cellular responses to epigenome modifiers an...

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Vydáno v:NPJ Precis Oncol
Hlavní autoři: Cardenas, Horacio, Jiang, Guanglong, Thomes Pepin, Jessica, Parker, J. Brandon, Condello, Salvatore, Nephew, Kenneth P., Nakshatri, Harikrishna, Chakravarti, Debabrata, Liu, Yunlong, Matei, Daniela
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897992/
https://ncbi.nlm.nih.gov/pubmed/31840082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-019-0103-4
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