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Expedient synthesis of E-hydrazone esters and 1H-indazole scaffolds through heterogeneous single-atom platinum catalysis

Unprotected E-hydrazone esters are prized building blocks for the preparation of 1H-indazoles and countless other N-containing biologically active molecules. Despite previous advances, efficient and stereoselective synthesis of these compounds remains nontrivial. Here, we show that Pt single atoms a...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Liu, Cuibo, Chen, Zhongxin, Yan, Huan, Xi, Shibo, Yam, Kah Meng, Gao, Jiajian, Du, Yonghua, Li, Jing, Zhao, Xiaoxu, Xie, Keyu, Xu, Haisen, Li, Xing, Leng, Kai, Pennycook, Stephen J., Liu, Bin, Zhang, Chun, Koh, Ming Joo, Loh, Kian Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897547/
https://ncbi.nlm.nih.gov/pubmed/31840074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay1537
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