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A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity
Curative cancer therapies are uncommon and nearly always involve multi-drug combinations developed by experimentation in humans; unfortunately, the mechanistic basis for the success of such combinations has rarely been investigated in detail, obscuring lessons learned. Here, we use isobologram analy...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6897534/ https://ncbi.nlm.nih.gov/pubmed/31742555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50036 |
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