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Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors as a First Step in Protection from Xenobiotics.

This mini-review examines the crucial importance of transcription factors as a first line of defense in the detoxication of xenobiotics. Key transcription factors that recognize xenobiotics or xenobiotic-induced stress such as reactive oxygen species (ROS), include AhR, PXR, CAR, MTF, Nrf2, NF-κB, a...

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Bibliographic Details
Published in:Nucl Receptor Res
Main Author: Baldwin, William S.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897393/
https://ncbi.nlm.nih.gov/pubmed/31815118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.32527/2019/101447
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