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Adaptive and Specialised Transcriptional Responses to Xenobiotic Stress in Caenorhabditis elegans Are Regulated by Nuclear Hormone Receptors

Characterisation of the pathways by which xenobiotics are metabolised and excreted in both target and non-target organisms is crucial for the rational design of effective and specific novel bioactive molecules. Consequently, we have investigated the induced responses of the model nematode Caenorhabd...

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Detalhes bibliográficos
Main Authors: Jones, Laura M., Rayson, Samantha J., Flemming, Anthony J., Urwin, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724934/
https://ncbi.nlm.nih.gov/pubmed/23922869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069956
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