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In-situ vaccination using focused ultrasound heating and anti-CD-40 agonistic antibody enhances T-cell mediated local and abscopal effects in murine melanoma
The success of melanoma immunotherapy is dependent on the presence of activated and functional T-cells in tumors. The objective of this study was to investigate the impact of local-focused ultrasound (FUS) heating (~42–45°C) and in-situ anti-CD-40 agonistic antibody in enhancing T-cell function for...
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| Publié dans: | Int J Hyperthermia |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6897315/ https://ncbi.nlm.nih.gov/pubmed/31795832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02656736.2019.1663280 |
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