Extradomain-B Fibronectin-Targeted Dextran-Based Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Probe for Detecting Pancreatic Cancer

A dextran-peptide conjugate was developed for magnetic resonance (MR) molecular imaging of pancreatic ductal adenocarcinoma (PDAC) through its overexpressed microenvironment biomarker, extradomain-B fibronectin (EDB-FN). This new agent consists of diamagnetic and biocompatible dextran and a targetin...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Han, Zheng, Zhang, Shuixing, Fujiwara, Kenji, Zhang, Jia, Li, Yuguo, Liu, Jing, van Zijl, Peter C. M., Lu, Zheng-Rong, Zheng, Lei, Liu, Guanshu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896991/
https://ncbi.nlm.nih.gov/pubmed/30938983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00161
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