Detecting acid phosphatase enzymatic activity with phenol as a chemical exchange saturation transfer magnetic resonance imaging contrast agent (PhenolCEST MRI)

Phenol contains an exchangeable hydroxyl proton resonant at 4.8 ppm from the resonance frequency of water in the (1)H nuclear magnetic resonance ((1)H NMR) spectrum, enabling itself to be detected at sub-mM concentration by either chemical exchange saturation transfer magnetic resonance imaging (CES...

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I publikationen:Biosens Bioelectron
Huvudupphovsmän: Zhang, Jia, Yuan, Yue, Han, Zheng, Li, Yuguo, van Zijl, Peter C. M., Yang, Xing, Bulte, Jeff W. M., Liu, Guanshu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717000/
https://ncbi.nlm.nih.gov/pubmed/31252256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2019.111442
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