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Total Synthesis and Structural Reassignment of Lyngbyaloside C Highlighted by Intermolecular Ketene Esterification

Lyngbyaloside C, a classic macrolide, isolated from Lyngbya bouilloni, has shown moderate anticancer activity against several cancer cell lines. Here, we report the first total synthesis and stereochemical configuration reassignment of lyngbyaloside C. The synthesis highlights a one-pot intermolecul...

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Bibliographic Details
Published in:Chemistry
Main Authors: Chang, Chia-Fu, Stefan, Eric, Taylor, Richard E.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896800/
https://ncbi.nlm.nih.gov/pubmed/26101039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201502132
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