KRAS Mutant Allele Fraction in Circulating Cell-Free DNA Correlates With Clinical Stage in Pancreatic Cancer Patients

Background: The research on circulating tumor DNA (ctDNA) in pancreatic cancer (PC) has emerged recently. Although the detection rate of the KRAS mutation in ctDNA was relatively consistent with that in tumor tissue, whether the KRAS mutant allele fraction (MAF) differed was still not reported. So f...

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Vydáno v:Front Oncol
Hlavní autoři: Wang, Zhe-Ying, Ding, Xiao-Qing, Zhu, Hui, Wang, Rui-Xian, Pan, Xiao-Rong, Tong, Jian-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896365/
https://ncbi.nlm.nih.gov/pubmed/31850201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01295
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