KRAS Mutant Allele Fraction in Circulating Cell-Free DNA Correlates With Clinical Stage in Pancreatic Cancer Patients

Background: The research on circulating tumor DNA (ctDNA) in pancreatic cancer (PC) has emerged recently. Although the detection rate of the KRAS mutation in ctDNA was relatively consistent with that in tumor tissue, whether the KRAS mutant allele fraction (MAF) differed was still not reported. So f...

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Publicado en:Front Oncol
Autores principales: Wang, Zhe-Ying, Ding, Xiao-Qing, Zhu, Hui, Wang, Rui-Xian, Pan, Xiao-Rong, Tong, Jian-Hua
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896365/
https://ncbi.nlm.nih.gov/pubmed/31850201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01295
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