The tyrosine 73 and serine 83 dephosphorylation of H1N1 swine influenza virus NS1 protein attenuates virus replication and induces high levels of beta interferon

BACKGROUND: Nonstructural protein 1 (NS1) is a virulence factor encoded by influenza A virus (IAV) that is expressed in the nucleus and cytoplasm of host cells during the earliest stages of infection. NS1 is a multifunctional protein that plays an important role in virus replication, virulence and i...

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Detaylı Bibliyografya
Yayımlandı:Virol J
Asıl Yazarlar: Cheng, Jinghua, Tao, Jie, Li, Benqiang, Shi, Ying, Liu, Huili
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896355/
https://ncbi.nlm.nih.gov/pubmed/31805964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-019-1255-0
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