Epidemiological pathology of Aβ deposition in the ageing brain in CFAS: addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches

Aβ-amyloid deposition is a key feature of Alzheimer’s disease, but Consortium to Establish a Registry for Alzheimer's Disease (CERAD) assessment, based on neuritic plaque density, shows a limited relationships to dementia. Thal phase is based on a neuroanatomical hierarchy of Aβ-deposition, and...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Wharton, S. B., Wang, D., Parikh, C., Matthews, F. E., Brayne, C., Ince, P. G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896261/
https://ncbi.nlm.nih.gov/pubmed/31806014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0858-4
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