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PipeMEM: A Framework to Speed Up BWA-MEM in Spark with Low Overhead

(1) Background: DNA sequence alignment process is an essential step in genome analysis. BWA-MEM has been a prevalent single-node tool in genome alignment because of its high speed and accuracy. The exponentially generated genome data requiring a multi-node solution to handle large volumes of data cu...

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Detalles Bibliográficos
Publicado en:Genes (Basel)
Main Authors: Zhang, Lingqi, Liu, Cheng, Dong, Shoubin
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896194/
https://ncbi.nlm.nih.gov/pubmed/31689965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10110886
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