hENT1 Testing in Pancreatic Ductal Adenocarcinoma: Are We Ready? A Multimodal Evaluation of hENT1 Status

Gemcitabine is still one of the standard chemotherapy regimens for pancreatic ductal adenocarcinoma (PDAC). Gemcitabine uptake into tumor cells is mainly through the human equilibrative nucleoside transport 1 (hENT1). It was therefore proposed as a potential predictive biomarker of gemcitabine effic...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Raffenne, Jerome, Nicolle, Remy, Puleo, Francesco, Le Corre, Delphine, Boyez, Camille, Marechal, Raphael, Emile, Jean François, Demetter, Peter, Bardier, Armelle, Laurent-Puig, Pierre, de Mestier, Louis, Paradis, Valerie, Couvelard, Anne, VanLathem, Jean Luc, MacKey, John R., Bachet, Jean-Baptiste, Svrcek, Magali, Cros, Jerome
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896053/
https://ncbi.nlm.nih.gov/pubmed/31752123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111808
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