hENT1 Testing in Pancreatic Ductal Adenocarcinoma: Are We Ready? A Multimodal Evaluation of hENT1 Status

Gemcitabine is still one of the standard chemotherapy regimens for pancreatic ductal adenocarcinoma (PDAC). Gemcitabine uptake into tumor cells is mainly through the human equilibrative nucleoside transport 1 (hENT1). It was therefore proposed as a potential predictive biomarker of gemcitabine effic...

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Опубликовано в: :Cancers (Basel)
Главные авторы: Raffenne, Jerome, Nicolle, Remy, Puleo, Francesco, Le Corre, Delphine, Boyez, Camille, Marechal, Raphael, Emile, Jean François, Demetter, Peter, Bardier, Armelle, Laurent-Puig, Pierre, de Mestier, Louis, Paradis, Valerie, Couvelard, Anne, VanLathem, Jean Luc, MacKey, John R., Bachet, Jean-Baptiste, Svrcek, Magali, Cros, Jerome
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896053/
https://ncbi.nlm.nih.gov/pubmed/31752123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111808
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