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Nucleocytoplasmic Shuttling of STATs. A Target for Intervention?

Signal transducer and activator of transcription (STAT) proteins are transcription factors that in the latent state are located predominantly in the cytoplasm. Activation of STATs through phosphorylation of a single tyrosine residue results in nuclear translocation. The requirement of tyrosine phosp...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ernst, Sabrina, Müller-Newen, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895884/
https://ncbi.nlm.nih.gov/pubmed/31752278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111815
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