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In Vivo Evidence for Voltage-Gated Sodium Channel Expression in Carcinomas and Potentiation of Metastasis

A wide body of evidence suggests that voltage-gated sodium channels (VGSCs) are expressed de novo in several human carcinomas where channel activity promotes a variety of cellular behaviours integral to the metastatic cascade. These include directional motility (including galvanotaxis), pH balance,...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Djamgoz, Mustafa B. A., Fraser, Scott P., Brackenbury, William J.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895836/
https://ncbi.nlm.nih.gov/pubmed/31661908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111675
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