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Voltage-gated sodium channels and metastatic disease

Voltage-gated Na(+) channels (VGSCs) are macromolecular protein complexes containing a pore-forming α subunit and smaller non-pore-forming β subunits. VGSCs are expressed in metastatic cells from a number of cancers. In these cells, Na(+) current carried by α subunits enhances migration, invasion an...

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Detalles Bibliográficos
Autor Principal: Brackenbury, William J.
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508774/
https://ncbi.nlm.nih.gov/pubmed/22992466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21910
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